Profile Response Detail

Molecular Profile Unknown unknown
Therapy MSC2490484A
Indication/Tumor Type Advanced Solid Tumor
Response Type no benefit
Create By spatt
Update By spatt

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown Advanced Solid Tumor no benefit MSC2490484A Phase I Actionable In a Phase I trial, MSC2490484A (M3814) demonstrated safety, but limited clinical activity, in patients with solid tumors (J Clin Oncol 35, 2017 (suppl; abstr 2556)). detail...
PubMed Id Reference Title Details
A multicenter phase I trial of the DNA-dependent protein kinase (DNA-PK) inhibitor M3814 in patients with solid tumors. Full reference...