Profile Response Detail

Molecular Profile TP53 positive
Therapy MVAp53
Indication/Tumor Type Advanced Solid Tumor
Response Type sensitive
Create By rliu
Update By smockus


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
TP53 positive Advanced Solid Tumor sensitive MVAp53 Phase I Actionable In a phase I study, Ankara (MVAp53) demonstrated safety and efficacy in patients with metastatic colon, gastric and pancreas cancer stained positive for p53 (J Clin Oncol 31, 2013 (suppl; abstr 3089)). detail...
PubMed Id Reference Title Details
A phase I study of an MVA vaccine targeting p53 in cancer. Full reference...