Profile Response Detail

Molecular Profile Unknown unknown
Therapy Temsirolimus + Neratinib
Indication/Tumor Type Advanced Solid Tumor
Response Type not applicable
Create By rliu
Update By cstatz

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown Advanced Solid Tumor not applicable Temsirolimus + Neratinib Phase I Actionable In a Phase I study, Nerlynx (neratinib) administered with Torisel (temsirolimus) was tolerable and demonstrated antitumor activity in multiple solid tumor types, including breast cancer and NSCLC (PMID: 24323026). 24323026
PubMed Id Reference Title Details
(24323026) Phase I study of neratinib in combination with temsirolimus in patients with human epidermal growth factor receptor 2-dependent and other solid tumors. Full reference...