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Molecular Profile Unknown unknown
Therapy KPT-9274
Indication/Tumor Type Advanced Solid Tumor
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown Advanced Solid Tumor not applicable KPT-9274 Phase I Actionable In a Phase I trial, KPT-9274 treatment resulted in stable disease in 29% (4/14) of patients with advanced solid tumors (Ann Oncol 2017, Vol 28, Suppl 5, Abstract # 374PD; NCT02702492). detail...
PubMed Id Reference Title Details
A first in human phase 1 study of KPT-9274, a first in class dual inhibitor of PAK4 and NAMPT, in patients with advanced solid malignancies or NHL Full reference...