Molecular Profile | Unknown unknown |
Therapy | KPT-9274 |
Indication/Tumor Type | Advanced Solid Tumor |
Response Type | not applicable |
Create By | tyin |
Update By | tyin |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References | Unknown unknown | Advanced Solid Tumor | not applicable | KPT-9274 | Phase I | Actionable | In a Phase I trial, KPT-9274 treatment resulted in stable disease in 29% (4/14) of patients with advanced solid tumors (Ann Oncol 2017, Vol 28, Suppl 5, Abstract # 374PD; NCT02702492). | detail... |
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PubMed Id | Reference Title | Details |
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A first in human phase 1 study of KPT-9274, a first in class dual inhibitor of PAK4 and NAMPT, in patients with advanced solid malignancies or NHL | Full reference... |