Profile Response Detail

Molecular Profile Unknown unknown
Therapy ISTH0047
Indication/Tumor Type kidney cancer
Response Type not applicable
Create By spatt
Update By cstatz

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown kidney cancer not applicable ISTH0047 Preclinical Actionable In a preclinical study, ISTH0047 reduced lung metastasis, but not primary tumor growth, in a mouse model of metastatic kidney cancer (PMID: 28911087). 28911087
PubMed Id Reference Title Details
(28911087) An antisense oligonucleotide targeting TGF-β2 inhibits lung metastasis and induces CD86 expression in tumor-associated macrophages. Full reference...