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Molecular Profile Unknown unknown
Therapy Relugolix
Indication/Tumor Type prostate cancer
Response Type not applicable

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown prostate cancer not applicable Relugolix Phase III Actionable In a Phase III trial (HERO), Relugolix (TAK-385) demonstrated superior serum testosterone suppression and maintenance of castration compared to Lupron (leuprolide) (96.7%, 601/622 vs 88.8%, 273/308, p<0.0001) in patients with androgen-sensitive advanced prostate cancer (PMID: 32469183; NCT03085095). 32469183
Unknown unknown prostate cancer not applicable Relugolix Phase II Actionable In a Phase II trial, Relugolix (TAK-385) resulted in decreased testosterone levels and greatly reduced prostate specific antigen levels after 24 weeks in prostate cancer patients (J Clin Oncol 34, 2016 (suppl 2S; abstr 200)). detail...
PubMed Id Reference Title Details
Second interim analysis (IA2) results from a phase II trial of TAK-385, an oral GnRH antagonist, in prostate cancer patients (pts). Full reference...
(32469183) Oral Relugolix for Androgen-Deprivation Therapy in Advanced Prostate Cancer. Full reference...