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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|FGFR1 amp NRAS amp||lung non-small cell carcinoma||resistant||Infigratinib||Preclinical - Cell culture||Actionable||In a preclinical study, amplification of NRAS was identified in a non-small cell lung cancer cell line harboring FGFR1 amplification that acquired resistance to Infigratinib (BGJ398) in culture (PMID: 28630215).||28630215|