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Molecular Profile Unknown unknown
Indication/Tumor Type Advanced Solid Tumor
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown Advanced Solid Tumor not applicable DM-CHOC-PEN Phase I Actionable In a Phase I trial, DM-CHOC-PEN (4-Demethyl-4-cholesteryloxycarbonylpenclomedine) treatment resulted in complete/partial response in 25% (3/12) of adolescent and young adult patients with advanced solid tumors (non-small cell lung cancer, acute lymphocytic leukemia, astrocytoma), improved quality of life, progression-free survival, and overall survival of 8-26 months (Mol Cancer Ther 2018;17(1 Suppl):Abstract nr A086; NCT02889445). detail...
PubMed Id Reference Title Details
Early clinical trial results for 4-demethyl-4-cholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) in adolescents and young adults (AYA) with cancers Full reference...