Profile Response Detail


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Molecular Profile Unknown unknown
Therapy Abiraterone + Onvansertib
Indication/Tumor Type prostate cancer
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown prostate cancer not applicable Abiraterone + Onvansertib Preclinical - Cell line xenograft Actionable In a preclinical study, Zytiga (abiraterone) and Onvansertib (PCM-075) synergistically inhibited growth of prostate cancer cells in cell line xenograft models (J Clin Oncol 36, 2018 (suppl 6S; abstr 369)). detail...
PubMed Id Reference Title Details
Combination of selective polo-like kinase 1 (PLK1) inhibitor PCM-075 with abiraterone in prostate cancer and non-androgen-driven cancer models. Full reference...