Profile Response Detail

Molecular Profile Unknown unknown
Therapy Panobinostat
Indication/Tumor Type colon cancer
Response Type not applicable
Create By smockus
Update By smockus

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colon cancer not applicable Panobinostat Preclinical Actionable In a preclinial study, Faridak (panobinostat) enhanced the cytotoxicity of TRAIL, tumor necrosis factor-related apoptosis-inducing ligand, in colon cancer cell lines (PMID: 21965751). 21965751
PubMed Id Reference Title Details
(21965751) Low-dose combinations of LBH589 and TRAIL can overcome TRAIL-resistance in colon cancer cell lines. Full reference...