Profile Response Detail

Molecular Profile BRAF mutant
Therapy Belvarafenib
Indication/Tumor Type colorectal cancer
Response Type sensitive
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
BRAF mutant colorectal cancer sensitive Belvarafenib Preclinical - Cell line xenograft Actionable In a preclinical study, Belvarafenib (HM95573) inhibited growth of BRAF mutant colorectal cancer cell lines in culture and in cell line xenograft models (Cancer Res 2015;75(15 Suppl):Abstract nr 2607). detail...
PubMed Id Reference Title Details
Antitumor activity of the selective RAF inhibitor HM95573 in solid tumors and hematologic malignancies Full reference...