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Molecular Profile Unknown unknown
Therapy Carboplatin + Nab-paclitaxel + Pembrolizumab
Indication/Tumor Type lung squamous cell carcinoma
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown lung squamous cell carcinoma not applicable Carboplatin + Nab-paclitaxel + Pembrolizumab FDA approved Actionable In a Phase III trial (KEYNOTE-407) that supported FDA approval, Keytruda (pembrolizumab) in combination with chemotherapy consisted of carboplatin and paclitaxel or nab-paclitaxel significantly improved overall survival (15.9 vs 11.3 months), progression-free survival (6.4 vs 4.8 months), and overall response rate (58% vs 35%) compared to placebo plus chemotherapy in patients with untreated metastatic squamous non-small cell lung cancer (J Clin Oncol 36, no. 15_suppl, 105-105; NCT02775435). detail... detail...
PubMed Id Reference Title Details
Phase 3 study of carboplatin-paclitaxel/nab-paclitaxel (Chemo) with or without pembrolizumab (Pembro) for patients (Pts) with metastatic squamous (Sq) non-small cell lung cancer (NSCLC). Full reference...
Keytruda (pembrolizumab) FDA Drug Label Full reference...