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Molecular Profile Unknown unknown
Therapy Darolutamide
Indication/Tumor Type prostate cancer
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown prostate cancer not applicable Darolutamide FDA approved Actionable In a Phase III trial (ARAMIS) that supported FDA approval, treatment with Nubeqa (darolutamide) resulted in improved median metastasis-free survival (40.4 vs 18.4 months, HR=0.41, p<0.001), overall survival (HR=0.71, 95% CI, 0.5-0.99, p=0.045), and time to pain progression (40.3 vs 25.4 months, HR=0.65, p<0.001) compared to placebo in non-metastatic castration-resistant prostate cancer patients (PMID: 30763142; NCT02200614). detail... 30763142
PubMed Id Reference Title Details
(30763142) Darolutamide in Nonmetastatic, Castration-Resistant Prostate Cancer. Full reference...
Nubeqa (darolutamide) FDA Drug Label Full reference...