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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|BCOR mut RUNX1 mut||acute myeloid leukemia||predicted - sensitive||Ruxolitinib||Preclinical - Patient cell culture||Actionable||In a preclinical study, co-occurrence of BCOR and RUNX1 mutations correlated with sensitivity to Jakafi (ruxolitinib) in patient-derived acute myeloid leukemia samples in an ex vivo assay (PMID: 30333627).||30333627|