Profile Response Detail

Molecular Profile ERBB2 amp
Therapy Afatinib
Indication/Tumor Type Advanced Solid Tumor
Response Type sensitive
Create By smockus
Update By


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
ERBB2 amp Advanced Solid Tumor sensitive Afatinib Phase II Actionable In a Phase II trial, Gilotrif (afatinib), demonstrated safety and efficacy in various advanced solid tumor patients with ERBB2 (HER2) amplification (PMID: 23775486). 23775486
PubMed Id Reference Title Details
(23775486) Phase 2 trial of afatinib, an ErbB family blocker, in solid tumors genetically screened for target activation. Full reference...