Profile Response Detail

Molecular Profile Unknown unknown
Therapy Adavosertib
Indication/Tumor Type colorectal cancer
Response Type not applicable
Create By smockus
Update By tyin


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colorectal cancer not applicable Adavosertib Preclinical - Cell line xenograft Actionable In a preclinical study, Adavosertib (MK-1775) inhibited cell proliferation and promoted DNA damage in a human colorectal cancer cell line in culture, and promoted tumor regression in xenograft models (PMID: 23699655). 23699655
PubMed Id Reference Title Details
(23699655) Preclinical evaluation of the WEE1 inhibitor MK-1775 as single-agent anticancer therapy. Full reference...