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Molecular Profile Unknown unknown
Therapy Docetaxel + RhFzd7
Indication/Tumor Type triple-receptor negative breast cancer
Response Type not applicable

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown triple-receptor negative breast cancer not applicable Docetaxel + RhFzd7 Preclinical - Cell line xenograft Actionable In a preclinical study, treatment with the combination of RhFzd7 and Taxotere (docetaxel) resulted in increased inhibition of proliferation and decreased tumor growth and neovascularization compared to either agent alone in cell line xenograft models of triple-negative breast cancer (PMID: 30096373). 30096373
PubMed Id Reference Title Details
(30096373) A novel recombinant human Frizzled-7 protein exhibits anti-tumor activity against triple negative breast cancer via abating Wnt/β-catenin pathway. Full reference...