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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|PALB2 Y551*||Advanced Solid Tumor||sensitive||Olaparib||Preclinical - Cell culture||Actionable||In a preclinical study, treatment with Lynparza (olaparib) resulted in decreased survival of TP53-knockout cells expressing PALB2 Y551* in culture (PMID: 31757951).||31757951|