Profile Response Detail

Molecular Profile Unknown unknown
Therapy AMG 900
Indication/Tumor Type Advanced Solid Tumor
Response Type not applicable
Create By smockus
Update By spatt

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown Advanced Solid Tumor not applicable AMG 900 Preclinical - Cell line xenograft Actionable In a preclinical study, AMG 900 inhibited the growth of a variety of human solid tumor cell lines in culture and inhibited tumor growth in cell line xenograft models of several tumor types including breast, colon, lung, pancreatic, and uterine cancer (PMID: 20935223). 20935223
PubMed Id Reference Title Details
(20935223) Preclinical evaluation of AMG 900, a novel potent and highly selective pan-aurora kinase inhibitor with activity in taxane-resistant tumor cell lines. Full reference...