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Molecular Profile Unknown unknown
Therapy TP-1454 + unspecified CTLA4 antibody
Indication/Tumor Type colorectal cancer
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colorectal cancer not applicable TP-1454 + unspecified CTLA4 antibody Preclinical Actionable In a preclinical study, TP-1454 treatment combined with an anti-CTLA4 antibody inhibited tumor growth and increased survival in a syngeneic mouse model of colorectal cancer (Mol Cancer Ther 2019;18(12 Suppl):Abstract nr B080). detail...
PubMed Id Reference Title Details
Abstract B080: PKM2 activation modulates metabolism and enhances immune response in solid tumor models Full reference...