Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|SRSF2 P95H||acute myeloid leukemia||sensitive||Indisulam||Preclinical - Cell culture||Actionable||In a preclinical study, an acute myeloid leukemia cell line engineered to express SRSF2 P95H from the endogenous locus demonstrated increased sensitivity to Indisulam (E7070) induced growth inhibition compared to parental cells in culture (PMID: 30799057).||30799057|