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Molecular Profile | Unknown unknown |
Therapy | MGD013 |
Indication/Tumor Type | triple-receptor negative breast cancer |
Response Type | not applicable |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
Unknown unknown | triple-receptor negative breast cancer | not applicable | MGD013 | Phase I | Actionable | In a Phase I trial, MGD013 treatment resulted in a partial response in 14.3% (2/14) and stable disease in 35.7% (5/14) of patients with triple-receptor negative breast cancer (J Clin Oncol 38: 2020 (suppl; abstr 3004); NCT03219268). | detail... |
PubMed Id | Reference Title | Details |
---|---|---|
A phase I, first-in-human, open-label, dose-escalation study of MGD013, a bispecific DART molecule binding PD‑1 and LAG‑3, in patients with unresectable or metastatic neoplasms. | Full reference... |