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Molecular Profile PIK3CA mutant
Therapy Carboxyamidotriazole Orotate
Indication/Tumor Type Advanced Solid Tumor
Response Type sensitive


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
PIK3CA mutant Advanced Solid Tumor sensitive Carboxyamidotriazole Orotate Phase I Actionable In a Phase I clinical trial, carboxyamidotriazole orotate treatment demonstrated some efficacy in patients with various solid tumors, including patients harboring PIK3CA mutations (J Clin Oncol 31, 2013 (suppl; abstr 2518)). detail...
PubMed Id Reference Title Details
A phase I study of carboxyamidotriazole orotate (CTO) in of advanced solid tumors. Full reference...