Profile Response Detail


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Molecular Profile FLT3 D835H
Therapy Dubermatinib
Indication/Tumor Type hematologic cancer
Response Type sensitive


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
FLT3 D835H hematologic cancer sensitive Dubermatinib Preclinical - Cell culture Actionable In a preclinical study, Dubermatinib (TP-0903) inhibited growth of transformed cells expressing FLT3 D835H in culture (PMID: 33268594). 33268594
PubMed Id Reference Title Details
(33268594) TP-0903 is active in models of drug-resistant acute myeloid leukemia. Full reference...