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Molecular Profile Unknown unknown
Therapy Ponatinib
Indication/Tumor Type lymphoid leukemia
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown lymphoid leukemia not applicable Ponatinib FDA approved Actionable In a Phase II clinical trial which supported FDA approval, Iclusig (ponatinib) was effective in promoting disease regression in 52% of patients with accelerated phase chronic myeloid leukemia, 31% of patients with blast phase chronic myeloid leukemia, and 41% of patients with Philadelphia chromosome positive acute lymphoblastic leukemia (PMID: 23935038). 23935038 detail...
PubMed Id Reference Title Details
(23935038) Ponatinib--a step forward in overcoming resistance in chronic myeloid leukemia. Full reference...
Iclusig (ponatinib) FDA Drug Label Full reference...