Profile Response Detail

Molecular Profile Unknown unknown
Therapy Imatinib
Indication/Tumor Type dermatofibrosarcoma protuberans
Response Type not applicable
Create By cms
Update By smockus

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown dermatofibrosarcoma protuberans not applicable Imatinib FDA approved Actionable In a Phase II clinical trial that supported FDA approval, treatment with Gleevec (imatinib) resulted in a median time-to-progression of 23.9 months, and complete response in 33% (4/12) and partial response in 50% (6/12) of patients with dermatofibrosarcoma protuberans (PMID: 18451237). 18451237 detail...
PubMed Id Reference Title Details
(18451237) Phase II, open-label study evaluating the activity of imatinib in treating life-threatening malignancies known to be associated with imatinib-sensitive tyrosine kinases. Full reference...
Gleevec (imatinib) FDA Drug Label Full reference...