Profile Response Detail


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Molecular Profile CDKN2A inact mut
Therapy unspecified immune checkpoint inhibitor
Indication/Tumor Type head and neck squamous cell carcinoma
Response Type not predictive


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
CDKN2A inact mut head and neck squamous cell carcinoma not predictive unspecified immune checkpoint inhibitor Clinical Study - Cohort Actionable In a retrospective analysis, homozygous deletion of CDKN2A or loss of function CDKN2A mutations in two cohorts of head and neck squamous cell carcinoma patients were not predictive of overall survival or time to treatment failure when treated with immune checkpoint inhibitors (PMID: 34074656). 34074656
PubMed Id Reference Title Details
(34074656) CDKN2A Alterations and Response to Immunotherapy in Solid Tumors. Full reference...