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Molecular Profile CDKN2A del
Therapy unspecified immune checkpoint inhibitor
Indication/Tumor Type lung non-small cell carcinoma
Response Type not predictive


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
CDKN2A del lung non-small cell carcinoma not predictive unspecified immune checkpoint inhibitor Clinical Study - Cohort Actionable In a retrospective analysis, homozygous deletion of CDKN2A or loss of function CDKN2A mutations in two cohorts of non-small cell lung cancer patients were not predictive of overall survival or time to treatment failure when treated with immune checkpoint inhibitors (PMID: 34074656). 34074656
PubMed Id Reference Title Details
(34074656) CDKN2A Alterations and Response to Immunotherapy in Solid Tumors. Full reference...