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Molecular Profile | FGFR2 - NRAP |
Therapy | Infigratinib |
Indication/Tumor Type | cholangiocarcinoma |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
FGFR2 - NRAP | cholangiocarcinoma | predicted - sensitive | Infigratinib | Case Reports/Case Series | Actionable | In a clinical case study, treatment with Truseltiq (infigratinib) resulted in stable disease for seven months in a patient with cholangiocarcinoma harboring an FGFR2-NRAP fusion (PMID: 34250419). | 34250419 |
PubMed Id | Reference Title | Details |
---|---|---|
(34250419) | Noninvasive Detection of Polyclonal Acquired Resistance to FGFR Inhibition in Patients With Cholangiocarcinoma Harboring FGFR2 Alterations. | Full reference... |