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Molecular Profile RET fusion
Therapy Selpercatinib
Indication/Tumor Type differentiated thyroid gland carcinoma
Response Type sensitive

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
RET fusion differentiated thyroid gland carcinoma sensitive Selpercatinib Guideline Actionable Retevmo (selpercatinib) is included in guidelines for patients with advanced or metastatic differentiated thyroid gland carcinoma harboring RET fusions (PMID: 31549998, PMID: 35491008; ESMO.org). 35491008 31549998 detail...
PubMed Id Reference Title Details
ESMO Clinical Practice Guidelines Full reference...
(35491008) ESMO Clinical Practice Guideline update on the use of systemic therapy in advanced thyroid cancer. Full reference...
(31549998) Thyroid cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†. Full reference...