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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||colorectal cancer||not applicable||INCB054329||Preclinical - Cell line xenograft||Actionable||In a preclinical study, INCB054329 promoted apoptosis and decreased MYC expression in colorectal cancer cell lines in culture and demonstrated anti-tumor activity in colorectal cancer cell line xenograft models (AACR; 2015. Abstract nr 3525).||detail...|
|PubMed Id||Reference Title||Details|
|The BET inhibitor INCB054329 is efficacious as a single agent or in combination with targeted agents in colorectal cancer models||Full reference...|