Profile Response Detail


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Molecular Profile BRAF V600E
Therapy Cetuximab + Encorafenib + Ulixertinib
Indication/Tumor Type colorectal cancer
Response Type predicted - sensitive


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
BRAF V600E colorectal cancer predicted - sensitive Cetuximab + Encorafenib + Ulixertinib Case Reports/Case Series Actionable In an expanded access program (ULI-EAP-100), Ulixertinib (BVD-523), Braftovi (encorafenib), and Erbitux (cetuximab) combination therapy resulted in a complete response in a patient with colorectal cancer harboring BRAF V600E (J Clin Oncol 40, no. 16_suppl (June 01, 2022) e15101; NCT04566393). detail...
PubMed Id Reference Title Details
Updated clinical outcomes from ULI-EAP-100, an intermediate expanded access program for ulixertinib (BVD-523). Full reference...