Profile Response Detail


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Molecular Profile FGFR2 C382R
Therapy Pemigatinib
Indication/Tumor Type breast cancer
Response Type predicted - sensitive


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
FGFR2 C382R breast cancer predicted - sensitive Pemigatinib Preclinical - Cell culture Actionable In a preclinical study, Pemazyre (pemigatinib) inhibited growth of mouse mammary epithelial cells expressing FGFR2 C287R (corresponding to C382R in human) in culture (PMID: 35948633). 35948633
PubMed Id Reference Title Details
(35948633) Truncated FGFR2 is a clinically actionable oncogene in multiple cancers. Full reference...