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Molecular Profile ARID1A dec exp
Therapy CPI-1205
Indication/Tumor Type urinary bladder cancer
Response Type sensitive

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
ARID1A dec exp urinary bladder cancer sensitive CPI-1205 Preclinical - Cell culture Actionable In a preclinical study, CPI-1205 inhibited viability of bladder cancer cell lines with ARID1A knockdown in culture (PMID: 35852858). 35852858
PubMed Id Reference Title Details
(35852858) ARID1A-deficient bladder cancer is dependent on PI3K signaling and sensitive to EZH2 and PI3K inhibitors. Full reference...