Profile Response Detail

Molecular Profile Unknown unknown
Therapy SAR260301
Indication/Tumor Type Advanced Solid Tumor
Response Type no benefit
Create By smockus
Update By cstatz

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown Advanced Solid Tumor no benefit SAR260301 Phase I Actionable In a Phase I trial, SAR260301 treatment in advanced solid tumor patients failed to inhibit the PI3K pathway due to rapid clearance, and therefore, was not recommended for further clinical analysis (PMID: 28976556; NCT01673737). 28976556 detail...
PubMed Id Reference Title Details
First-in-human phase I trial of the PI3Kb-selective inhibitor SAR260301 in patients with advanced solid tumors (NCT01673737). Full reference...
(28976556) First-in-human trial of the PI3Kβ-selective inhibitor SAR260301 in patients with advanced solid tumors. Full reference...