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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|ATM Q628Pfs*7 ATM I1581Nfs*5 ATM A2843V||colon adenocarcinoma||sensitive||RP-3500||Preclinical - Cell line xenograft||Actionable||In a preclinical study, RP-3500 inhibited viability in a colon adenocarcinoma cell line harboring ATM Q628Pfs*7, ATM I1581Nfs*5, and ATM A2843V in culture, and inhibited tumor growth in a cell line xenograft model (PMID: 34911817).||34911817|