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Molecular Profile ALK C1156Y
Therapy Alectinib
Indication/Tumor Type Advanced Solid Tumor
Response Type sensitive

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
ALK C1156Y Advanced Solid Tumor sensitive Alectinib Preclinical Actionable In a preclinical study, ALK C1156Y was sensitive to Alecensa (alectinib) in an in vitro enzyme assay (PMID: 21575866). 21575866
PubMed Id Reference Title Details
(21575866) CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant. Full reference...