Profile Response Detail

Molecular Profile NPM1-ALK
Therapy TAE684
Indication/Tumor Type Advanced Solid Tumor
Response Type sensitive
Create By c-seddy
Update By tyin


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
NPM1-ALK Advanced Solid Tumor sensitive TAE684 Preclinical - Cell culture Actionable In a preclinical study, TAE684 inhibited proliferation of transformed cells expressing NPM1-ALK in culture (PMID: 20207848). 20207848
PubMed Id Reference Title Details
(20207848) ALK-positive large B-cell lymphomas with cryptic SEC31A-ALK and NPM1-ALK fusions. Full reference...