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Molecular Profile | BRAF V600X |
Therapy | Vemurafenib |
Indication/Tumor Type | cholangiocarcinoma |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
BRAF V600X | cholangiocarcinoma | sensitive | Vemurafenib | Phase II | Actionable | In a Phase II clinical trial, treatment with Zelboraf (vemurafenib) resulted in partial response in 12% (1/8) and stable disease in 50% (4/8) of cholangiocarcinoma patients with BRAF V600 mutations (PMID: 26287849). | 26287849 |
PubMed Id | Reference Title | Details |
---|---|---|
(26287849) | Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations. | Full reference... |