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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|CBL mutant||myelodysplastic/myeloproliferative neoplasm||not applicable||N/A||Clinical Study||Prognostic||In clinical analyses, mutations in CBL were associated with adverse prognosis in patients with chronic myelomonocytic leukemia (PMID: 26230957, PMID: 23690417, PMID: 19901108).||26230957 19901108 23690417|
|PubMed Id||Reference Title||Details|
|(26230957)||An international data set for CMML validates prognostic scoring systems and demonstrates a need for novel prognostication strategies.||Full reference...|
|(23690417)||Prognostic score including gene mutations in chronic myelomonocytic leukemia.||Full reference...|
|(19901108)||Mutations of e3 ubiquitin ligase cbl family members constitute a novel common pathogenic lesion in myeloid malignancies.||Full reference...|