Profile Response Detail

Molecular Profile FGFR2 amp
Therapy Debio 1347
Indication/Tumor Type colorectal cancer
Response Type sensitive
Create By tyin
Update By spatt


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
FGFR2 amp colorectal cancer sensitive Debio 1347 Preclinical Actionable In a preclinical study, Debio 1347 inhibited proliferation of colorectal cancer cell lines harboring FGFR2 amplification in culture (PMID: 25169980). 25169980
PubMed Id Reference Title Details
(25169980) The fibroblast growth factor receptor genetic status as a potential predictor of the sensitivity to CH5183284/Debio 1347, a novel selective FGFR inhibitor. Full reference...