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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||Advanced Solid Tumor||not applicable||OSU03012||Phase I||Actionable||In a Phase I trial, OSU03012 (AR-12) treatment demonstrated safety and resulted in stable disease in 6% (2/30) of patients with advanced solid tumors, however, a new formulation was recommended due to limited absorption of the drug (J Clin Oncol 31, 2013 (suppl; abstr 2608)).||detail...|
|PubMed Id||Reference Title||Details|
|A first-in-human phase I trial of AR-12, a PDK-1 inhibitor, in patients with advanced solid tumors||Full reference...|