Profile Response Detail

Molecular Profile Unknown unknown
Therapy INCB040093 + Itacitinib
Indication/Tumor Type Hodgkin's lymphoma
Response Type not applicable
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown Hodgkin's lymphoma not applicable INCB040093 + Itacitinib Phase I Actionable In a Phase I trial, INCB040093 and INCB039110 combination treatment resulted in complete response in 22% (2/9) of Hodgkin's lymphoma patients, with an objective response rate of 67% (J Clin Oncol 33, 2015 (suppl; abstr 8558)). detail...
PubMed Id Reference Title Details
A phase 1 study of INCB040093, a PI3K? inhibitor, alone or in combination with INCB039110, a selective JAK1 inhibitor: Interim results from patients (pts) with relapsed or refractory (r/r) classical Hodgkin lymphoma (cHL). Full reference...