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Molecular Profile | Unknown unknown |
Therapy | LY2109761 + Paclitaxel |
Indication/Tumor Type | triple-receptor negative breast cancer |
Response Type | not applicable |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
Unknown unknown | triple-receptor negative breast cancer | not applicable | LY2109761 + Paclitaxel | Preclinical | Actionable | In a preclinical study, LY2109761 and Taxol (paclitaxel) worked synergistically to inhibit the growth of triple-receptor negative breast cancer cell lines in culture (PMID: 20576088). | 20576088 |
PubMed Id | Reference Title | Details |
---|---|---|
(20576088) | RNA interference (RNAi) screening approach identifies agents that enhance paclitaxel activity in breast cancer cells. | Full reference... |