Profile Response Detail


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Molecular Profile Unknown unknown
Therapy Erlotinib + Glesatinib
Indication/Tumor Type gastroesophageal junction adenocarcinoma
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown gastroesophageal junction adenocarcinoma not applicable Erlotinib + Glesatinib Phase I Actionable In a Phase I trial, 38% (3/8) of patients with gastroesophageal cancer remained on study for approximately 12-26 cycles with Glesatinib (MGCD265) and Tarceva (erlotinib) combination therapy (J Clin Oncol 30, 2012 (suppl; abstr e13602)). detail...
PubMed Id Reference Title Details
MGCD265, a multitargeted oral tyrosine kinase receptor inhibitor of Met and VEGFR, in combination with erlotinib in patients with advanced solid tumors. Full reference...