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Molecular Profile | Unknown unknown |
Therapy | Cisplatin + YM155 |
Indication/Tumor Type | rhabdomyosarcoma |
Response Type | not applicable |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
Unknown unknown | rhabdomyosarcoma | not applicable | Cisplatin + YM155 | Preclinical - Cell line xenograft | Actionable | In a preclinical study, the combination of YM155 and Platinol (cisplatin) inhibited tumor growth in a human rhabdomyosarcoma cell line xenograft model (PMID: 26983495). | 26983495 |
PubMed Id | Reference Title | Details |
---|---|---|
(26983495) | Survivin selective inhibitor YM155 promotes cisplatin‑induced apoptosis in embryonal rhabdomyosarcoma. | Full reference... |