Profile Response Detail

Molecular Profile Unknown unknown
Therapy OPB-31121
Indication/Tumor Type Advanced Solid Tumor
Response Type not applicable
Create By tyin
Update By tyin

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown Advanced Solid Tumor not applicable OPB-31121 Phase I Actionable In a Phase I trial, OPB-31121 treatment resulted in stable diseases in 44% (8/18) of patients with advanced solid tumors, and tumor shrinkage in 2 patients (1 colon cancer, 1 rectal cancer) (PMID: 25715763). 25715763
PubMed Id Reference Title Details
(25715763) Phase I Study of OPB-31121, an Oral STAT3 Inhibitor, in Patients with Advanced Solid Tumors. Full reference...