Molecular Profile | Unknown unknown |
Therapy | OPB-31121 |
Indication/Tumor Type | Advanced Solid Tumor |
Response Type | not applicable |
Create By | tyin |
Update By | tyin |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References | Unknown unknown | Advanced Solid Tumor | not applicable | OPB-31121 | Phase I | Actionable | In a Phase I trial, OPB-31121 treatment resulted in stable diseases in 44% (8/18) of patients with advanced solid tumors, and tumor shrinkage in 2 patients (1 colon cancer, 1 rectal cancer) (PMID: 25715763). | 25715763 |
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PubMed Id | Reference Title | Details |
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(25715763) | Phase I Study of OPB-31121, an Oral STAT3 Inhibitor, in Patients with Advanced Solid Tumors. | Full reference... |