Profile Response Detail

Molecular Profile Unknown unknown
Therapy Ch282-5 + Oxaliplatin
Indication/Tumor Type colon cancer
Response Type not applicable
Create By spatt
Update By c-romase


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colon cancer not applicable Ch282-5 + Oxaliplatin Preclinical - Cell line xenograft Actionable In a preclinical study, the combination of ch282-5 and Eloxatin (oxaliplatin) inhibited cell growth in human and mouse colon cancer cell lines in culture, and the combination synergized to inhibit tumor growth in mouse colon cancer cell line xenograft models (PMID: 26515494). 26515494
PubMed Id Reference Title Details
(26515494) A Novel Bioavailable BH3 Mimetic Efficiently Inhibits Colon Cancer via Cascade Effects of Mitochondria. Full reference...