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Molecular Profile Unknown unknown
Therapy Nelfinavir + Radiotherapy
Indication/Tumor Type rectum cancer
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown rectum cancer not applicable Nelfinavir + Radiotherapy Phase I Actionable In a Phase I trial, the combination of Nelfinavir and radiotherapy resulted in median tumor cell density reduction from 24.3% at baseline to 9.2%, and tumor regression in 56% (5/9) of rectal cancer patients (PMID: 26861457). 26861457
PubMed Id Reference Title Details
(26861457) Clinical Trial of Oral Nelfinavir before and during Radiation Therapy for Advanced Rectal Cancer. Full reference...