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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|MSH6 mutant||colorectal cancer||not applicable||N/A||Clinical Study||Diagnostic||Germline mutations in MSH6 are associated with microsatellite instability in colorectal cancer (CRC), and are diagnostic for Lynch syndrome (hereditary nonpolyposis colorectal cancer) in colorectal cancer patients (PMID: 26582061; PMID: 19125127).||26582061 19125127|
|PubMed Id||Reference Title||Details|
|(26582061)||Comparison of Prediction Models for Lynch Syndrome Among Individuals With Colorectal Cancer.||Full reference...|
|(19125127)||EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome.||Full reference...|